Chemical Biology Letters

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Chemical Biology Letters
Editors
Prof. Keykavous Parang
Chapman University Editor (USA)
Dr. B.S. Chhikara,
University of Rhode Island Executive Managing Editor
Dr. R. Dabur,
M.D. University Associate Editor (India)

ISSN 2347–9825

Chemical Biology Letters is now indexed in WHO’s HINARI (see details at Chemical Biology Letters on HINARI ).

The Chemical Biology Letter is an international journal that provides a rapid forum for publication of quality original research at the interface of chemistry and biology. Chemical biology letters covers the scientific ideas and approaches of chemistry, biology and allied interdisciplinary areas such as medicinal chemistry, drug discovery, drug delivery, biosensor, protein chemistry, biological chemistry, biomolecules, bio-technology, biomedical, molecular biology and other allied areas covering chemistry and biology for better understanding of biological phenomenon at molecular level. The journal invite research articles from the community of chemical biologists.
See Five selected articles in Medicinal Chemistry / Biomedical Sciences

 

Recent Aricle
Latest Articles
Earlier
A series of novel 2-(3-aryl/alkylaminopropoxy)-12-aryl-9,10-dihydro-8H- benzo[a]xanthen-11-one derivatives were synthesized from 2-hydroxy-12-aryl 9,10-dihydro-8H-benzo[a]xanthen-11-ones by reaction with 1-bromo-3-chloropropane in presence of K2CO3 in dry acetone under reflux followed by reaction with aryl/alkyl amines in presence of KI in dry DMF at 100oC. Structures have been confirmed by spectroscopic analysis. All the newly [...]
Source: Chem Biol Lett
A new class of 1,3,4-thiadiazole derivatives 8a-i incorporating imidazo [1,2-b] pyridazine and thiazolidinone moieties were synthesized by the reaction of arylidene derivatives of 1,3,4-thiadiazoles 2-amine having imidazo [1,2-b] pyridazine moiety (Schiff base) 7a-i with thioglycolic acid. Schiff base 7a-i were synthesized by the reaction of 1,3,4-thiadiazoles 2-amine having imidazo [...]
Source: Chem Biol Lett
Antibiotic resistant bacteria (ABR) is an alarming issue and it has to be eliminated before enter into the environment. The role of efflux pump inhibitor, reserpine – a plant alkaloid in reducing the antibiotic resistance in Staphylococcus sp., Streptococcus sp. and Micrococcus sp. from poultry litter were evaluated. [...]
Source: Chem Biol Lett
A new series of N-(6-methoxybenzo[d]thiazol-2-yl)-2-substituted phenyl-1H-benz[d]imidazole-1-carbothioamide derivatives (5a-5h) has been synthesized and evaluated for antibacterial, antifungal and antimalarial effects. All these compounds were characterized and screened for their in vitro antimicrobial activity against selected bacterial and fungal strains. Titled compounds were also evaluated for their antimalarial activity against P. falciparum. [...]
Source: Chem Biol Lett
Plants produce an enormous number of phytochemicals as a part of their primary as well as secondary metabolism of those many could be of therapeutic value especially antimicrobial application to human beings. Majority of the isolated antimicrobials pertain to chemical groups namely, phenolics, terpenes, alkaloids and polypeptides, and exhibit multiple [...]
Source: Chem Biol Lett
The Swine influenza is a highly contagious respiratory disease caused by one of several swine influenza A viruses. The viral replication complex of H1N1, formed by three proteins PA, PB1 and PB2, plays a major role in host adaptation and subsequent infection. The conserved interaction sites of these three proteins [...]
Source: Chem Biol Lett
Outer membrane proteins (OMPs) are distinctive features of Gram-negative bacteria. Apart from their structural role, they play a crucial role in host pathogen interaction, virulence and pathogenesis of bacteria. Upon interaction with the host immune cells, OMPs stimulate production of proinflammatory molecules that may result in an uncontrolled inflammation, leading [...]
Source: Chem Biol Lett
An outburst of Ebola Hemorrhagic Fever (EHF) in recent years is a challenge towards health preparedness of India. Oseltamivir is the only frontline drug used in the treatment of Ebola hemorrhagic fever. In order to enhance preparedness again Ebola virus induced fever it is required to identify more derivatives with [...]
Source: Chem Biol Lett
H5N1 causes high mortality in domestic poultry. It is the causative agent of H5N1 flu and is the world's largest current pandemic threat. Haemagglutinin (HA) is a surface glycoprotein of the virus which facilitates viral attachment to target cell and its entry. HA frequently accumulates mutation to escape immune response [...]
Source: Chem Biol Lett
Tuberculosis is a major health problem, which is not only fatal, if left untreated; but also spreads rapidly and is persistent in nature. This makes it one of the world's deadliest diseases. There is a recorded history describing prevalence of TB-like symptoms since ancient times. During 1980s, the disease became [...]
Source: Chem Biol Lett

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