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Recent Articles published in ISP Journals

Herein we describe a simple method for the synthesis of Baylis-Hillman adducts and their acetates by utilizing inexpensively available cashew nut shell liquid (CNSL) natural resources. Furthermore, by using a molecular hybridization approach, a series of novel pyrimidine scaffolds (15a-15t) were synthesized via utilizing Baylis-Hillman acetates derived from cashew nut [...]
Mon, Feb 12, 2018, Continue reading at the source
In the present investigation, total twenty two thermophilic lignolytic bacterial cultures were isolated from various sources using Nutrient Agar (NA) and Minimal Salt Medium (MSM) medium with Lignin Alkali (1.0 g/L) by incubating at pH 7 and 50°C for 48 hrs. These isolates were characterized by special reference to their [...]
Sat, Feb 03, 2018, Continue reading at the source
The present study is intended to ascertain the quality of water for public consumption and other life supporting activities by way of assessing pollution indices such as Carlson's trophic state index (C-TSI), eutrophication index (EI), organic pollution index (OPI) and comprehensive pollution index (CPI).The study has been carried out for [...]
Sat, Feb 03, 2018, Continue reading at the source
The current concepts of cancer therapy are moving towards personalized treatment regimen aiming to reduce toxicity and improve efficacy of therapeutic agents. With the development of molecular imaging and targeted therapies personalized care has received a shot in the arm. However, these developments are not without challenges. Drug delivery, metabolism, [...]
Sat, Jan 13, 2018, Continue reading at the source
Hyperparathyroidism (HPTH) is a condition in which the level of parathyroid hormone in blood is raised. Gold standard for the diagnosis of HPTH is a measurement of serum parathyroid hormone levels, accompanied by testing serum calcium levels, to differentiate between primary and secondary HPTH. The first line of treatment with [...]
Sat, Jan 13, 2018, Continue reading at the source
In this study, we have prepared a novel, dual-biomarker, targeting ligand having high affinity and specificity for PSMA/GRPr receptors that are expressed on most prostate cancers. [DUPA-6-Ahx-Lys(DOTA)-6-Ahx-RM2] was synthesized and the new conjugate was metallated macroscopically with GaCl3, InCl3, and LuCl3 to form [DUPA-6-Ahx-Lys(M-DOTA)-6-Ahx-RM2] (where M = Ga, In, [...]
Sat, Jan 13, 2018, Continue reading at the source
In this paper we report the synthesis of 68Ga labeled NODAGA-Erlotinib for imaging of EGFR over-expressing tumors. NODAGA-Erlotinib conjugate was synthesized by reaction of the terminal alkyne of Erlotinib using Cu catalyzed click reaction. The conjugate was then radiolabeled with 68Ga in high radiochemical yields. The 68Ga NODAGA-Erlotinib conjugate also [...]
Sat, Jan 13, 2018, Continue reading at the source
The demand for higher fuel economy and lower exhaust gas emissions of CI engine cannot be achieved by just using mechanically governed fuel injection systems. The electronically operated fuel injection system is the heart of a CI engine and has become one of the essential technologies to control critical in [...]
Fri, Dec 22, 2017, Continue reading at the source
Earlier reported supramolecular entities of antibiotics (SMEAs) synthesized from various antibiotic drugs were tested to find out their antimicrobial properties i.e. Antibacterial activity against Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa), and Antifungal activity against Candida albicans, Aspergillus flavis and Candida glaberata), and showed varying degree of percentage inhibition. Antibiotics [...]
Thu, Dec 21, 2017, Continue reading at the source

JMNS and CBL articles