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Recent Articles published in ISP Journals

In this study, we have prepared a novel, dual-biomarker, targeting ligand having high affinity and specificity for PSMA/GRPr receptors that are expressed on most prostate cancers. [DUPA-6-Ahx-Lys(DOTA)-6-Ahx-RM2] was synthesized and the new conjugate was metallated macroscopically with GaCl3, InCl3, and LuCl3 to form [DUPA-6-Ahx-Lys(M-DOTA)-6-Ahx-RM2] (where M = Ga, In, [...]
Thu, Dec 14, 2017, Continue reading at the source
In this paper we report the synthesis of 68Ga labeled NODAGA-Erlotinib for imaging of EGFR over-expressing tumors. NODAGA-Erlotinib conjugate was synthesized by reaction of the terminal alkyne of Erlotinib using Cu catalyzed click reaction. The conjugate was then radiolabeled with 68Ga in high radiochemical yields. The 68Ga NODAGA-Erlotinib conjugate also [...]
Thu, Dec 14, 2017, Continue reading at the source
Chronic obstructive pulmonary disease (COPD) is internationally preferred term encompassing chronic bronchitis, asthma and emphysema. Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction with breathing-related symptoms such as chronic cough, exertional dyspnea, expectoration, and wheeze. These symptoms may occur in conjunction with airway hyper responsiveness and may be [...]
Fri, Nov 03, 2017, Continue reading at the source
A series of novel 2-(3-aryl/alkylaminopropoxy)-12-aryl-9,10-dihydro-8H- benzo[a]xanthen-11-one derivatives were synthesized from 2-hydroxy-12-aryl 9,10-dihydro-8H-benzo[a]xanthen-11-ones by reaction with 1-bromo-3-chloropropane in presence of K2CO3 in dry acetone under reflux followed by reaction with aryl/alkyl amines in presence of KI in dry DMF at 100oC. Structures have been confirmed by spectroscopic analysis. All the newly [...]
Mon, Sep 18, 2017, Continue reading at the source
The present study intends to compare and correlate serum & salivary glucose level in healthy & diabetic individuals. A total of 500 subjects were examined, of which 429 were healthy & 71 were confirmed diabetics. Post–prandial blood and salivary samples were analyzed. Mann-Whitney test using Pearson correlation was applied, which [...]
Sun, Aug 27, 2017, Continue reading at the source
Abstract: In the present research work we concentrated on the structure elucidation of new hetero polyacid salts: Zirconium Antimonoarsanotungstate Zr[SbAsW] salt synthesized at variable pH using sol-gel route. An instrumental technique, FTIR was used to assign the structural aspects to the compound. Physical characterization involves the determination of [...]
Sat, Aug 26, 2017, Continue reading at the source
The effect of La for Ba and Co for Sn substitution on the properties of Barium stanate i.e. solid solution of LaCoO3 with BaSnO3 of the type Ba1-xLaxSn1-xCoxO3 is investigated for x ≤ 0.30.The powders are prepared using high temperature solid state reaction method for composition x ≤ 0.30. The [...]
Thu, Aug 10, 2017, Continue reading at the source
The discovery of bacterial-communication systems (quorum-sensing systems), which orchestrate important temporal events during the infection process, has afforded a novel opportunity to ameliorate bacterial infection by means other than growth inhibition. In this study three different assays were performed; Las-A staphylolytic assay, anti-swarming assay, pyocyanin assay. In the anti-swarming activity, [...]
Mon, Jul 24, 2017, Continue reading at the source
Gastroesophagus reflux disease, acidity and hearts burning are the most common problems, which can be overcome by the raft forming in-situ gel system containing combination of H2 antagonist and GABAB antagonist as well as raft forming agents (alginate, pectin etc.). GERD develops when the reflux of the gastric contents occur [...]
Mon, Jul 03, 2017, Continue reading at the source
A new class of 1,3,4-thiadiazole derivatives 8a-i incorporating imidazo [1,2-b] pyridazine and thiazolidinone moieties were synthesized by the reaction of arylidene derivatives of 1,3,4-thiadiazoles 2-amine having imidazo [1,2-b] pyridazine moiety (Schiff base) 7a-i with thioglycolic acid. Schiff base 7a-i were synthesized by the reaction of 1,3,4-thiadiazoles 2-amine having imidazo [...]
Tue, Jun 27, 2017, Continue reading at the source

JMNS and CBL articles

 


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