Synthesis of novel 2-(3-aryl/alkylamino propoxy)-12-aryl xanthene derivatives as antifungal and antibacterial agents

By admin By Bhaskara Nand, Kalawati Meena, Shruti Gupta, J.M. Khurana, Amita Malik, Chetan Sharma, Harsh Panwar A series of novel 2-(3-aryl/alkylaminopropoxy)-12-aryl-9,10-dihydro-8H– benzo[a]xanthen-11-one derivatives were synthesized from 2-hydroxy-12-aryl 9,10-dihydro-8H-benzo[a]xanthen-11-ones by reaction with 1-bromo-3-chloropropane in presence of K2CO3 in dry acetone under reflux followed by reaction with aryl/alkyl amines in presence of KI in dry DMF at 100oC. […]

Source:: http://pubs.iscience.in/synthesis-of-novel-2-3-arylalkylamino-propoxy-12-aryl-xanthene-derivatives-as-antifungal-and-antibacterial-agents/