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Schiff base transition metal complexes for N-Arylation of heterocycles under mild conditions

Gautam Anna Gaikwad, Sujit Sambhaji Hegade, Ganpatrao Narsing Mulik


A series of schiff base transition metal complexes [M(2L)X2] where M= Co (II), Ni(II), Cu(II) and Zn(II), X= Cl and  L= 2-Phenyl 3- benzoylamino  1,2 -Dihydro Quinazolin-4(3H)-one (PBADQ) were synthesized by the reaction of Schiff base PBADQ and transition  metal salts CoCl2.6H2O, NiCl2.6H2O, CuCl2.2H2O and ZnCl2. The Schiff base ligand L and complexes 1-4 were characterized by C, H, N elemental analysis, IR, NMR spectral studies. The catalytic activity of these complexes was tested for N-Arylation of Indole and Benzoimidazole and observed that all the complexes worked as the efficient catalysts for the N-Arylation of Indole and Benzoimidazole with Bromobenzene and its derivatives at moderate reaction conditions in DMSO.






KeywordsQuinazolinone Schiff base, transition metal complexes, N-Arylation


Corresponding author: Tel.: +91 2343221632; fax: +91 2343221632.



Quinazolinone Schiff base; transition metal complexes; N-Arylation

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