schiff bases synthesis

Methane Sulphonic acid catalyzed an efficient synthesis of Schiffs Bases

Pramod Kulkarni, Ramesh Gawade, Kaluram Kanade


Methane sulphonic acid was found an efficient catalyst for synthesis of Schiff bases. The Schiff bases have been synthesised from condensation reaction between carbonyl compound and primary aromatic amines. The merits of this protocol is simple and inexpensive, biodegradable catalyst, short reaction time, simplicity of the reaction and workup process, high yield of products.


Carbonyl compound; primary amine; Methane sulphonic acid; condensation reaction; Schiff base

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ISSN 2348 – 1889