Plants and their extracts have been extensively studied for their efficacy in therapeutic applications. Their Essential Oils (EOs) are responsible for the majority of biological properties such as anticancer, antibacterial and antimicrobial, antioxidant, anti-inflammatory, and cardio-protective. The utilization of natural compounds is gaining a lot of attention these days. These oils act as natural alternatives to the modern medical system to cure the illness that occurs in the biological system. This review provides an overview of the impact of the two most important plant-based oils: Mustard oil and Olive oil, the role of their components in different biological activities leading to their therapeutic applications. Their intake provides health benefits by controlling the symptoms of the diseases that involve cancer, bacterial infections, inflammation, cardiovascular, and some other common diseases. Most of the results come from in vitro and in vivo studies. However, their use in clinical studies is very little known.
Author: 9853121882ya
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2. B.K. Sharma. Ph.D. Dissertation, Thesis Title, Cornell University, 1995.
3. R. Hussain, D. Shinkoi. Title of book like Synthesis and application of ionic liquid, John Wiley & Sons: New York, 2010.
4. R.S. Buchanod, D.K. Reddy. In Selective Organic Transformations; T.R. Thyagarajan, Ed.; Integrated science: New York, 2002; Vol. 2, pp 1–95.
5. G.L. Loyale, U.S. Patent 5 934 456, 1998; Chem. Abstr. 1998, 65, 2870.
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Journal of Molecular Chemistry
The Journal of Molecular Chemistry is a peer reviewed international journal at the heart of chemistry, meant to cover research at all stages from molecule design, synthesis to applications. The journal publishes research in chemistry at molecular level to applications in biological or physical/materials field. It covers the Organic Chemistry, synthetic organic chemistry, catalysis, new methodologies, natural product synthesis, new reaction pathways, peptide synthesis, small molecule synthesis, Chemistry research, chemical technology and other allied areas covering advances in chemistry and exploration of molecular applications in biology, medicine, polymer, materials and environment.
Journal of Molecular Chemistry
https://pubs.thesciencein.org/journal/index.php/jmc
The journal publishes full length research articles, review article, tutorial articles, expert opinions from all field of organic chemistry and allied chemistry research including Synthetic Organic Chemistry, Catalysis, Medicinal Chemistry, Materials Chemistry, Heterocyclic Chemistry, Macrocyclic chemistry, Polymer Chemistry, NanoChemistry, Chemical Engineering and all other research advances related to new chemistry development. The chemistry research fraternity is invited to submit their next excellent article on journal site
https://pubs.thesciencein.org/journal/index.php/jmc
Author guidelines and article templates are provided on the journal site.
Molecular Chemistry Letters
The Molecular Chemistry Letters is an international journal meant to provide a rapid forum for publication of quality original research from molecule design, synthesis and applications with major coverage in organic chemistry and interdisciplinary chemistry research. The Molecular Chemistry Letters covers the synthetic organic chemistry, catalysis, new methodologies, natural product synthesis, new reaction pathways, peptide synthesis, small molecule synthesis, Polymer chemistry, Medicinal Chemistry, Materials Chemistry, Chemistry Biology Interface research, chemical technology, green chemistry, environmental chemistry and other allied areas covering advances in chemistry.
Molecular Chemistry Letters
https://pubs.thesciencein.org/journal/index.php/mcl
The journal publishes short communications (letters), research articles, review article, tutorial articles, expert opinions from all field of organic chemistry and allied chemistry research including Synthetic Organic Chemistry, Catalysis, Heterocyclic Chemistry, Macrocyclic chemistry, Polymer Chemistry, NanoChemistry, Chemical Engineering and all other research advances related to new chemistry development. The chemistry research fraternity is invited to submit their next excellent article on journal site
https://pubs.thesciencein.org/journal/index.php/mcl
Author guidelines and article templates are provided on the journal site.
2021 Reviewers Chemical Biology Letters
The list of reviewers for Chemical Biology Letters. The names of selected reviewers who showed reservation in displaying their name on this page have been omitted from this list.
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Dr. Vu Duc Canh University of Tokyo |
Dr. Almando Geraldi Universitas Airlangga |
Dr. Brijesh Rathi University of Delhi (4 articles) |
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Dr. Kavindra Kumar Kesari Aalto University, Espoo, Finland |
Dr. Manoj K. Tripathi Central Institute of Agricultural Engineering |
Dr. Sumit Kumar DCR University of Science and Technology (7 articles) |
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Dr Elif Sahin Yeni Yüzyil Üniversitesi, Turkey (2 articles) |
Dr. Sobhana Sahoo Vidyasagar College for Women, University of Calcutta (3 articles) |
Dr. Pallav Sengupta MAHSA University, Malaysia (7 articles) |
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Dr. Prasenjit Chaudhuri Sister Nivedita Government Degree College (2 articles) |
Dr. Sermin Bicer Yeni Yüzyil Üniversitesi, Turkey (2 articles) |
Dr. Koushik Bhattacharya Rungta College of Dental Science and Research |
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Dr. Kesab Raj Joshi Tribhuvan University |
Dr. Varsha Mehra Shaheed Rajguru College of Applied Sciences for Women, University of Delhi |
Dr. Sulagna Dutta MAHSA University, Malaysia (5 articles) |
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Dr. Indrakant Singh Deshbandhu College, University of Delhi |
Dr. Beena Negi University of Delhi |
Dr. Manisha Khatri Shaheed Rajguru College of Applied Sciences for Women, University of Delhi |
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Prof. Anil Kumar Birla Institute of Technology and Science |
Dr. Suresh Dua Kurukshetra University |
Prof. Rambir Singh Mizoram University |
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Prof. Sujata Mishra Siksha’O’Anusandhan University |
Dr. Pooja Singh University of Delhi |
Prof. Tulay Irez Yeni Yüzyil Üniversitesi, Turkey |
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Dr. Suvendu Ghosh Post Graduate Department of Physiology, Hooghly Mohsin College |
Dr. Arijit Chakraborty The Assam Royal Global University |
Prof. Ajaikumar Kunnumakkara Indian Institute of Technology Guwahati |
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Dr. Helen Antony University of Kerala |
Dr. Chai Theam Ooi MAHSA University, Malaysia |
Dr. Anand Dev Tiwari Cleveland Clinic Foundation, USA |
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Dr. Ajmer Singh Grewal Guru Govind Singh College of Pharmacy |
Dr. Rajiv Kharab Amity University, Noida |
Dr. Poonam Miranda House, University of Delhi (3 articles) |
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Dr. Amit K. Kushwaha Indian Institute of Science Education and Research Bhopal |
Dr. Ajay Kumar Banaras Hindu University |
Dr. Kuldeep Singh Maharshi Markandeshwar University |
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Prof. Rajiv Dahiya The University of West Indies |
Dr. Shaoyong Ke National Biopesticide Engineering Research Institute, China |
Dr. Gauravi Deshpande Digital Imaging Core, Lerner Research Institute, Cleveland |
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Dr. Ronaldo Nascimento de Oliveira Federal Rural University of Pernambuco (UFRPE), Brazil |
Baoen Chen, PhD Life Sciences Institute, Zhejiang University, China |
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| more to be updated |
CANCER BIOLOGY: Advances and Challenges
The global population health status indicates the rapid increase in the incidence of cancer, the leading ailment responsible for high mortality rates. A surge in cancer cases has been observed due to various reasons such as lifestyle related behaviors, carcinogenic exposures, occupational hazards and genetic epidemiology. This makes cancer literacy and knowledge an important step against cancer. Taking the various issues into consideration, we need to define a roadmap towards effective programs for comprehensive cancer control and awareness. Cancer awareness makes early detection of cancer that further helps in the management and treatment. The awareness also paves a path towards prevention of cancer by living a healthy lifestyle. The aim of the conference is to understand the latest successful interventions in prevention, diagnosis, timely-accessed treatment, care and control of cancer. Now, the time is to unite and stand against the global cancer burden and to move towards the advancement of global cancer control that leaves no one behind.
The University of Delhi, Deshbandhu College ( https://www.deshbandhucollege.ac.in/) is going to host a 3-day International Conference on “CANCER BIOLOGY: Advances & Challenges” https://sites.google.com/db.du.ac.in/health-2021 on 11-13 Nov 2021 (Registration link: https://forms.gle/H5ig2kx5NbfiXytz5) with aim towards a global collaboration between scientists, research scholars and students working on various aspects of cancer biology from different research organizations, medical institutions and reputed Universities, to share their ideas and discuss the possible solutions. The selected full-length articles from speakers, participants and other scholars will be published in special thematic issue.
This issue will provide the information about recent researches related to the cancer biology including the advances and challenges. The goal of cancer research is to develop safe and effective methods to prevent, detect, diagnose, treat, and therapeutic the diseases. This aims to strengthen the action and impact of the cancer research on national, regional and international scales through its advancement which spans the full spectrum of cancer – from prevention and treatment to palliative care.
Themes
- Cancer Epidemiology and Health Outcomes
- Cancer Genetics
- Carcinogenic Exposure
- Computational Oncology
- Metastasis and Drug Resistance
- Cancer Diagnosis, Therapy and Treatment
- System Biology
- Other related themes
Editors
Important Dates
Full Article Submission date- November 30, 2021
Issue completion date – December 31, 2021
Submission
Interested scholars should submit their article (prepared according to author guidelines in the journal article template) on the journal site https://pubs.thesciencein.org/journal/index.php/cbl (Or on http://pubs.iscience.in/journal/index.php/cbl )
(In cover letters to editor mention that article is for consideration in special issue). Authors can also submit their article manuscript directly to guest editors for preliminary editorial processing.
Clinical status of potential drugs used for COVID-19 treatment and recent advances in new therapeutics – A review
COVID-19, a perilous disease caused by SARS-CoV-2, has brought a massive damage to humankind, and turned into a global catastrophe. It was first reported in Wuhan, China in December 2019 and since then has been a constant source of worry for the scientists and the medical world, due to the carnage it has caused globally. Extensive clinical studies are being carried to explore drug therapy and prophylaxis to combat this pestilence. It is still an excessively big challenge for the scientists and pharmacological industry to develop potential drugs for the treatment of this deadly virus. At present though no specific drug has been identified as a perfect cure for this zoonotic disease, medical practitioners are using the therapy of repurposing of drugs for the treatment. Systemic research was carried out through e-resources to identify drugs for the treatment of COVID-19. A recent proposal of 2-DG drug as a cure for COVID-19 has also been discussed in this review.
A comparative study of isothermal nucleic acid amplification methods for SARS-CoV-2 detection at point-of-care
COVID-19, caused by the novel coronavirus SARS-CoV-2, has put most of the world under lockdown. Despite approved vaccines, COVID-19 cases, hospitalizations, and deaths have remained on the rise. Rapid diagnosis and necessary public health measures are still key parts to contain the pandemic. Here, the colorimetric isothermal nucleic acid amplification tests (iNAATs) for SARS-CoV-2 detection based on loop-mediated isothermal amplification (LAMP), cross-priming amplification (CPA), and polymerase spiral reaction (PSR) were designed and compared in performance for the first time. The findings showed that, for the detection of SARS-CoV-2 genomic-RNA, LAMP outperformed both CPA and PSR, exhibiting the limit of detection (LOD) of roughly 43.14 copies/reaction. The results can be read with the naked eye within 45 minutes, without cross-reactivity to closely related coronaviruses. The direct detection of SARS-CoV-2 RNA in simulated specimens by iNAATs was also successful. Additionally, the lyophilized reagents for LAMP reactions maintained the sensitivity and LOD of the liquid assays. The colorimetric LAMP assay was validated using clinical samples, showing 98.1% sensitivity and 100% specificity upon using extracted samples and 82.4% sensitivity and 86.2% specificity upon using unextracted specimens. The results indicate that the direct colorimetric LAMP assay developed is highly suitable for detecting SARS-CoV-2 at point-of-care.
Testosterone in the pathogenesis of tuberculosis
Tuberculosis is a leading cause of death from infectious diseases worldwide with more than 1.5 million deaths occurring annually. Males have been known to be more susceptible to tuberculosis than females. Sex hormones could be an important factor governing this gender bias. Here, we discuss the evidence that testosterone may be a crucial factor in male susceptibility to tuberculosis considering that testosterone impairs important factors which have a significant bearing on the outcome of tuberculosis. We also discuss possible underlying mechanisms through which testosterone modulates the immune response that is necessary for host resistance to tuberculosis. We discuss various models that have helped to uncover the role of testosterone in the outcome of infection by M. tuberculosis. Studying the role of testosterone on the various components that constitute the immune response to the disease have provided valuable insights into the sexual dichotomy observed in male bias in tuberculosis morbidity.
Resistin and visfatin: ‘connecting threads’ of immunity, energy modulations and male reproduction
Adipokines, mostly produced by white adipose tissues, have been established to be endocrine factors which are also essential in energy homeostasis. More recently, their contribution in fertility regulation has been recommended. Resistin as well as visfatin are unique adipocyte-derived signaling chemicals whose expressions enhance in advanced obesity and are implicated in insulin resistance as well as type-2 diabetes. They are also found to be immune modulators and may participate in aggravating inflammatory responses which may partly explain obesity-mediated systemic inflammation. They are yet much less explored adipokines with potential to regulate metabolic rate, immune homeostasis as well as fertility. These adipokines are shown to be expressed in the hypothalamus in an area in charge of energy balance. Evidence suggest that they can potentially affect the hypothalamo-pituitary-gonadal (HPG) axis thereby modulating reproductive functions. They are also found to be expressed highly by the testes. In rodents, resistin and visfatin may positively modulate Leydig cell number and steroidogenesis. Additionally, visfatin exists in the human spermatozoa and may play role in the sperm maturation. However, reports on the impact of resistin and visfatin on human male fertility are inconsistent. In this article, we review the available literature on the role resistin and visfatin on male reproduction and integrate the mechanisms to discuss if they act as sensor for body energy dyshomeostatis and modulate male reproductive functions as per the metabolic status.