Chemical Biology Letters

Chemical Biology LettersEditors
Prof. Keykavous Parang
Chapman University Editor (USA)
Dr. B.S. Chhikara,
University of Rhode Island Executive Managing Editor
Dr. R. Dabur,
M.D. University Associate Editor (India)
ISSN 2347–9825
The Chemical Biology Letter is an international journal that provides a rapid forum for publication of quality original research at the interface of chemistry and biology. Chemical biology letters covers the scientific ideas and approaches of chemistry, biology and allied interdisciplinary areas such as medicinal chemistry, drug discovery, drug delivery, biosensor, protein chemistry, biological chemistry, biomolecules, bio-technology, biomedical, molecular biology and other allied areas covering chemistry and biology for better understanding of biological phenomenon at molecular level. The journal invite research articles from the community of chemical biologists.

Chemical Biology Letters is now indexed in WHO’s HINARI (see details at Chemical Biology Letters on HINARI ).
See Five selected articles in Medicinal Chemistry / Biomedical Sciences

Recent ArticlesNews

2017 Vol 4 Issue 1

Development and validation of pharmacophore and QSAR models for influenza PB2 inhibitors
Deepak Kumar Behera, Pabitra Mohan Behera, Laxmikanta Acharya, Anshuman Dixit
Chem. Biol. Lett., 2017, 4(1), 1-8

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Fighting with Gram-negative enemy: Can outer membrane proteins aid in the rescue?
Anubhav Tamrakar, Amit Kumar Singh, Meenal Chodhrary, Prashant Kodgire
Chem. Biol. Lett., 2017, 4(1), 9-19

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Identification of immunodominant epitopes in the HA2 subunit of H5N1 haemagglutinin by immunoassay using synthetic peptides as antigens
Khangembam Victoria Chanu, Dimpal Thakuria, Richa Sood, Atul K Pateriya, Sandeep Bhatia, Satish Kumar
Chem. Biol. Lett., 2017, 4(1), 20-26

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Homology modeling and docking studies of VP24 protein of Ebola virus with an antiviral drug and its derivatives
Deepti Sharma, Navneet sharma, Mallika Pathak, Riya Sharma, Prateek Tyagi, Raman Chawla, Mitra Basu, Himanshu Ojha
Chem. Biol. Lett., 2017, 4(1), 27-32

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Trials and tribulations in tuberculosis research: Can plant based drug(s) be the solution?
Smita Mishra, Manisha Khatri, Varsha Mehra
Chem. Biol. Lett., 2017, 4(1), 33-47

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Antimicrobials in Higher Plants: classification, mode of action and bioactivities
Ishwar Singh
Chem. Biol. Lett., 2017, 4(1), 48-62

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2016 Vol 3 Issue 2

Application of Porphyrin nanomaterials in Photodynamic therapy
Pratibha Kumari, Renu Gautam, Archana Milhotra
Chem. Biol. Lett., 2016, 3(2), 32-37
Porphyrin Nanoparticles
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Synthesis of novel Imidazo [1,2-b] pyridazine derivatives and study of their biomedicinal efficacy
Ashish Bhatt, Rajesh Kumar Singh, Ravi Kant
Chem. Biol. Lett., 2016, 3(2), 38-43

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Morin augmented the metabolism and detoxification of ethanol: effects on TGF-β and the collagen accumulation
Saravanan Nadanam, Anbu Singaravelu, Padma Jayabalan, Niyas Ahamed Md Iqbal
Chem. Biol. Lett., 2016, 3(2), 44-51

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Synthesis, characterization and evaluation of prodrugs of ciprofloxacin clubbed with benzothiazoles through N-Mannich base approach
Mona Piplani, Avtar Chand Rana, Prabodh Chander Sharma
Chem. Biol. Lett., 2016, 3(2), 52-57

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Biosystematics of the Dioscorea species of western ghats using chemical and molecular tools
A. Rafeeq, K.B. Rameshkumar, N.S. Pradeep
Chem. Biol. Lett., 2016, 3(2), 58-63

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2016 Vol 3 Issue 1

An overview of lignans with special reference to podophyllotoxin, a cytotoxic lignan
Saptarshi Hazra, Sharmila Chattopadhyay
Chem. Biol. Lett., 2016, 3(1), 1-8
lignans podophyllotoxins
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Chemical Evolution and Origin of Life: A Review
Avnish Kumar Arora, Kuldeep Singh, Vivek Sheel Jaswal, Raman Singh
Chem. Biol. Lett., 2016, 3(1), 9-17
Evolution of life
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1,5-Benzothiazepine: Bioactivity and targets
Rajneesh Kaur, Raman Singh, Kuldeep Singh
Chem. Biol. Lett., 2016, 3(1), 18-31

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2015 Vol 2 Issue 2

Recent advances in development of Inhibitors of Dengue infection
Poonam Bhargava, Nisha Aggarwal
Chem. Biol. Lett., 2015, 2(2), 22-29
Dengue inhibitor drugs
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Liesegang patterns, growth kinetics, inhibition and dissolution of calcium phosphate: A constituent of renal stone
Alpana Tripathi, Gopal ji Srivastavaa, Sashank Srivastava, Ishwar Das
Chem. Biol. Lett., 2015, 2(2), 30-40
calcium phosphate crystal formation
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Comparative study of antibacterial activity of standard antibiotic with silver nanoparticles synthesized using ocimum tenuiflorum and garcinia mangostana leaves
Nikesh Gupta, Chetna Gupta, Sandeep Sharma, Rakesh Kumar Sharma, H. B. Bohidar
Chem. Biol. Lett., 2015, 2(2), 41-44
nanoparticle synthesis
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2015 Vol 2 Issue 1

Evaluation of inhibition of protein tyrosine phosphatase 1B by calixarene-based α-ketophosphonic acids
Viacheslav Trush, Sergiy Cherenok, Vsevolod Tanchuk, Vitaly Kalchenko, Andriy Vovk
Chem. Biol. Lett., 2015, 2(1), 1-5
Calixarene-kinase docking
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Evaluation of anti-hyperglycemic effect of Gracilaria corticata extract in Normal and Streptozotocin-induced Diabetic rats
Subashini Sekar, Pugalendi Viswanathan K, Baskaran Kishnan, Kripa Kavasseri Ganesan
Chem. Biol. Lett., 2015, 2(1), 6-11
anti-diabetic effect of plant extract
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Characterization of podophyllotoxin biosynthetic pathway and future prospect of podophyllotoxin production from Podophyllum hexandrum Royle
Dipto Bhattacharyya, Sharmila Chattopadhyay
Chem. Biol. Lett., 2015, 2(1), 12-21
podophyllotoxin biosynthetic pathway
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2014 Vol 1 Issue 2

Effects of 1,3-di-O-substituted-myo-inositol derivatives on the antiproliferation and caspase-3 activity of HCT-116 and HL-60 cells
Noriyuki Hatae, Satoe Yamauchi, Takafumi Saeki, Ichiro Suzuki, Tominari Choshi, Satoshi Hibino, Chiaki Okada, Yutaka Watanabe, Eiko Toyota
Chem. Biol. Lett., 2014, 1(2), 40-43

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3D-QSAR and molecular docking studies of ATP-competitive Akt inhibitors with the scaffold 4-(piperazin-1-yl)pyrimidine
Xie Wencheng, Zhang Linna, Yin Yanzhen, Yang Dezhi, Zhao Guisen
Chem. Biol. Lett., 2014, 1(2), 44-54

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Recent advances in PET imaging of folate receptor positive diseases
Qingshou Chen, Ping Wang, Philip S Low, Sumith A Kularatne
Chem. Biol. Lett., 2014, 1(2), 55-65

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Control of carbohydrate and lipid metabolism by NRF-1 and sirtuins: Implications on type 2 diabetes and obesity
Zane Ferreira, Ademola Ayeleso, Emmanuel Mukwevho
Chem. Biol. Lett., 2014, 1(2), 66-76

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Perspectivity of bifunctional chelating agents in chemical, biological and biomedical applications
Bhupender S. Chhikara, Sumit Kumar, Nidhi Jain, Anil Kumar, Rajiv Kumar
Chem. Biol. Lett., 2014, 1(2), 77-103

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2014 Vol 1 Issue 1

Calmodulin dependent protein kinase (CaMK)-II activation by exercise regulates omega-3 polyunsaturated fatty acids biosynthesis in rat skeletal muscle
Jitcy S Joseph, Emmanuel Mukwevho
Chem. Biol. Lett., 2014, 1(1), 1-10

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Tetrahedral Hydroxyethylamine: A Privileged Scaffold in Development of Antimalarial Agents
Brijesh Rathi, Ph.D., Prem Prakash Sharma, R P Singh
Chem. Biol. Lett., 2014, 1(1), 11-13

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Comparative global epidemiology of HIV infections and status of current progress in treatment
Jyoti Singh, Bhupender S. Chhikara
Chem. Biol. Lett., 2014, 1(1), 14-32

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Monoamine Oxidase Inhibitors for Neurological Disorders: A review
Ram Singh, Geetanjali ., Naveen Sharma
Chem. Biol. Lett., 2014, 1(1), 33-39

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Text Abst

Earlier
A series of novel 2-(3-aryl/alkylaminopropoxy)-12-aryl-9,10-dihydro-8H- benzo[a]xanthen-11-one derivatives were synthesized from 2-hydroxy-12-aryl 9,10-dihydro-8H-benzo[a]xanthen-11-ones by reaction with 1-bromo-3-chloropropane in presence of K2CO3 in dry acetone under reflux followed by reaction with aryl/alkyl amines in presence of KI in dry DMF at 100oC. Structures have been confirmed by spectroscopic analysis. All the newly [...]
Source: Chem Biol Lett
A new class of 1,3,4-thiadiazole derivatives 8a-i incorporating imidazo [1,2-b] pyridazine and thiazolidinone moieties were synthesized by the reaction of arylidene derivatives of 1,3,4-thiadiazoles 2-amine having imidazo [1,2-b] pyridazine moiety (Schiff base) 7a-i with thioglycolic acid. Schiff base 7a-i were synthesized by the reaction of 1,3,4-thiadiazoles 2-amine having imidazo [...]
Source: Chem Biol Lett
Antibiotic resistant bacteria (ABR) is an alarming issue and it has to be eliminated before enter into the environment. The role of efflux pump inhibitor, reserpine – a plant alkaloid in reducing the antibiotic resistance in Staphylococcus sp., Streptococcus sp. and Micrococcus sp. from poultry litter were evaluated. [...]
Source: Chem Biol Lett
A new series of N-(6-methoxybenzo[d]thiazol-2-yl)-2-substituted phenyl-1H-benz[d]imidazole-1-carbothioamide derivatives (5a-5h) has been synthesized and evaluated for antibacterial, antifungal and antimalarial effects. All these compounds were characterized and screened for their in vitro antimicrobial activity against selected bacterial and fungal strains. Titled compounds were also evaluated for their antimalarial activity against P. falciparum. [...]
Source: Chem Biol Lett
Plants produce an enormous number of phytochemicals as a part of their primary as well as secondary metabolism of those many could be of therapeutic value especially antimicrobial application to human beings. Majority of the isolated antimicrobials pertain to chemical groups namely, phenolics, terpenes, alkaloids and polypeptides, and exhibit multiple [...]
Source: Chem Biol Lett
The Swine influenza is a highly contagious respiratory disease caused by one of several swine influenza A viruses. The viral replication complex of H1N1, formed by three proteins PA, PB1 and PB2, plays a major role in host adaptation and subsequent infection. The conserved interaction sites of these three proteins [...]
Source: Chem Biol Lett
Outer membrane proteins (OMPs) are distinctive features of Gram-negative bacteria. Apart from their structural role, they play a crucial role in host pathogen interaction, virulence and pathogenesis of bacteria. Upon interaction with the host immune cells, OMPs stimulate production of proinflammatory molecules that may result in an uncontrolled inflammation, leading [...]
Source: Chem Biol Lett
An outburst of Ebola Hemorrhagic Fever (EHF) in recent years is a challenge towards health preparedness of India. Oseltamivir is the only frontline drug used in the treatment of Ebola hemorrhagic fever. In order to enhance preparedness again Ebola virus induced fever it is required to identify more derivatives with [...]
Source: Chem Biol Lett
H5N1 causes high mortality in domestic poultry. It is the causative agent of H5N1 flu and is the world's largest current pandemic threat. Haemagglutinin (HA) is a surface glycoprotein of the virus which facilitates viral attachment to target cell and its entry. HA frequently accumulates mutation to escape immune response [...]
Source: Chem Biol Lett
Tuberculosis is a major health problem, which is not only fatal, if left untreated; but also spreads rapidly and is persistent in nature. This makes it one of the world's deadliest diseases. There is a recorded history describing prevalence of TB-like symptoms since ancient times. During 1980s, the disease became [...]
Source: Chem Biol Lett
Earlier
The list of journals approved by UGC, University Grant Commission, New Delhi Journals no. on UGC are provided here for researchers quick reference. Sr. No. Journal No. Journal Name Link 3440 49349 Chemical Biology Letters 6337 47927 Journal of Materials NanoScience 6512 49358 Journal of Biomedical and Therapeutic Sciences 4703 [...]
Source: ISP Updates
Special Issue on Nuclear Medicine Journal Name: Chemical Biology Letters Editor(s): Dr. Anil K. Mishra, Scientist G Nuclear Medicine, a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease have been highly successful in diagnosis of difficult to detect diseases and therapy of various [...]
Source: ISP Updates
The complementary free subscription is available for the researchers, authors, reviewers. You can get your free subscription to Print version of the journals for one year completely free and also completely free online subscription for future on your recommendation to your institute / library and subsequent subscription thereby institute / [...]
Source: ISP Updates
List of high impact factor, peer reviewed, international journals in NanoMedicine [...]
Source: ISP Updates
Journal Name : Journal of Integrated Science and Technology Publisher Integrated Science Journal Issues per volume/year Two Frequency Biannual Editorial Board Members Multinational Journal Type International Journal International Serial Number – ISSN 2321–4635 Start Year 2013 Impact Factor (2013) 2.5333 Article Published (2013): 015 Citations recorded: 038 * Journal Link: [...]
Source: ISP Updates

 

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