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A Comparative study on Glucose Levels in Serum and Saliva of Patients with Diabetes Mellitus and Healthy Individuals at Mullana Area
Abstract
The present study intends to compare and correlate serum & salivary glucose level in healthy & diabetic individuals. A total of 500 subjects were examined, of which 429 were healthy & 71 were confirmed diabetics. Post–prandial blood and salivary samples were analyzed. Mann-Whitney test using Pearson correlation was applied, which was statistically significant (P < .001). To conclude, glucose concentration in saliva is higher in diabetics than in healthy individuals. Moreover the changes in serum glucose concentration are followed by the changes in salivary glucose concentration. Thus saliva can be used as an adjunct diagnostic tool in diabetes mellitus.
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P. Trinder Determination of glucose in blood using Glucose oxidase with an alternative oxygen receptor. Ann Clin Biochem 1969, 6, 24-25.
R.J. Henry, R.L. Dryer. Standard methods of clinical chemistry. New York, Academic Press, 1963. p. 205-37.
E. Raabo, T.C. Terkildsen. On the enzymatic determination of blood glucose. Scand J Clin Lab Invest 1960, 12, 402-407.
B.H. Ginsberg An Overview of minimally invasive technologies. Clin Chem 1992,38,1596-600.
C. Jurysta, C. Nicaise, S. Cetik, K. Louchami, W.J. Malaisse, A. Sener Glucose transport by acinar cells in rat parotid glands. Cell Physiol Biochem 2012, 29, 325-30.
C.O. Reuterving, G. Reuterving, E. Hägg, T. Ericson Salivary flow rate and salivary glucose concentration in patients with diabetes mellitus influence of severity of diabetes. Diabete. Metab. 1987, 13, 457-62.
A.M. Darwazeh, T.W. MacFarlane, A. McCuish, P.J. Lamey. Mixed salivary glucose levels and candidal carriage in patients with diabetes mellitus. J. Oral. Pathol. Med. 1991, 20, 280-3.
A.A. Borg, D. Birkhed, K. Berntorp, F. Lindgärde, L. Matsson. Glucose concentration in parotid saliva after glucose/food intake in individuals with glucose intolerance and diabetes mellitus. Eur. J. Oral. Sci. 1998, 106, 931-7.
S. Aydin. A comparison of Ghrelin, Glucose, Alpha-amylase and Protein levels in saliva from diabetics. J. Biochem. Mo.l Biol. 2007, 40, 29-35.
C. Jurysta, N. Bulur, B. Oguzhan, I. Satman, T.M. Yilmaz, W.J. Malaisee, A. Sener. Salivary glucose concentration and excretion in normal and diabetic subjects. J. Biomed. Biotechnol. 2009, 2009, 1-6.
S. S. Priya, G. O. Bharani, M. Nagalingam, M. Jayanthi, U. Kanagavalli Potential of salivary protein as a biomarker in prognosis of diabetes mellitus. J Pharm Res 2011, 4(7), 2228-2229.
A. Panda, R. Venkatapathy, O. Nirima. Glucose estimation in the salivary secretion of diabetes mellitus patients. Diabetics. Metab. Syndr. Obes. 2012, 5, 149-154.
V.V. Naik, S. Yasmin, G.S. Pilli, M.N. Mishra. Comparison and correlation of glucose levels in serum and saliva of patients with diabetes mellitus. Ind. J. Public. Health. Res. Dev. 2011, 2.
M.S.M. Soares, M.M.V. Batista-Filho, M.J. Pimentel, I.A. Passos, K.E. Chimenos. Determination of salivary glucose in healthy adults. Med Oral Patol. Cir. Bucal. 2009, 14, e510-13.
S. Amer, M. Yousuf, P.Q. Siddiqui, J. Alam. Salivary glucose concentrations in patients with diabetes mellitus– a minimally invasive technique for monitoring blood glucose levels. Pak. J. Pharm. Sci. 2001, 14, 33-37.
L.N. Forbat, R.E. Collins, G.K. Maskell, P.H. Sönksen. Glucose concentrations in parotid fluid and venous blood of patients attending a diabetic clinic. J. R. Soc. Med. 1981, 74, 725-8.
C. Carda, N. Mosquera-Lloreda, L. Salom, M.E. Gomez de Ferraris, A. Peydró. Structural and functional salivary disorders in type 2 diabetic patients. Med. Oral. Patol. Oral. Cir. Bucal. 2006, 11, 309-14.
A. Hedge, R. Shenoy, P. D’Mello, A. Smitha, A. Tintu, P. Manjrekar. Alternative markers of glycemic status in diabetes mellitus. Biomed. Res. 2010, 21, 252-256.
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