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Conductive carbon nanotubes based polyaniline/polypyrrole
polymer nanocomposite (CNT-PANI-PPy) film was electrochemically
synthesized on graphite electrode using cyclic voltammetry. CNT-PANI-PPy
film formed a biocompatible environment to entrap enzyme molecule and
used as biosensor for pesticide detection. This study shows that enzyme
based conductive polymer nanocomposite film itself acts as a mediator.
Carbon nanotubes promote electron transfer reactions in presence of
Acetythiocholine chloride (ATCl) as a substrate at a lower potential and
catalyzed the electrochemical oxidation of enzymatically formed
thiocholine. Surface morphology was studied by scanning electron
microscopy which shows a porous structure of the modified film
beneficial for enzyme immobilization. Electrochemical behavior of the
fabricated electrodes evaluated through cyclic voltammetry and
electrochemical impedance spectroscopy. The detection of pesticide
(acephate) was performed by chronoamperometry and the limit of detection
(LOD) of acephate was found to be 0.007 ppm concentration which is
Conductive carbon nanotubes based polyaniline/polypyrrole copolymer nanocomposite (CNT-PANI-PPy) film was electrochemically synthesized on graphite electrode using cyclic voltammetry. CNT-PANI-PPy film formed a biocompatible environment to entrap enzyme molecule and used as biosensor for pesticide detection. This study shows that enzyme based conductive copolymer nanocomposite film itself acts as a mediator. Carbon nanotubes promote electron transfer reactions in presence of acetylcholine chloride (ATCl) as a substrate at a lower potential and catalyzed the electrochemical oxidation of enzymatically formed thiocholine. Surface morphology was studied by scanning electron microscopy which shows a porous structure of the modified film beneficial for enzyme immobilization. Electrochemical behavior of the fabricated electrodes evaluated through cyclic voltammetry and electrochemical impedance spectroscopy. The detection of pesticide (acephate) was performed by chronoamperometry and the limit of detection (LOD) of acephate was found to be 0.007 ppm concentration which is quite low.
#NanoCatalysis covers the development in new #chemistry for #nanocatalysts synthesis and applications. The chemistry in the field of nanocatalysis and nanocatalysts is advancing at a fast pace, #high-impact and bringing the new methodologies, chemical procedures for synthesis of nanocatalysts along with development of new type of nanocatalysts. The application field of #nanochemistry of catalysis is spreading to new areas including new nanocatalysis, surface chemistry of nanocatalysts, refining and development of catalysts for existing procedures, new nanoconjugates for higher catalytic activity, nanophysics of catalytic materials, new organic nanocatalysts, solution chemistry of nanocatalysts, and so on. A special issue covering the recent advances in chemistry of nanocatalysis will cover following fields:
Carbon based nanocatalysts: Nanofullerenes, Carbon Nanotubes, Graphene,
Nanocatalysis – development of new nanocatalysts and applications thereof.
Nanoscience chemistry of metal catalyst materials
Chemistry of Nanoenergy materials
NanoChips (semiconductor designing and development using new materials chemistry)
Nanocatalysts/nanomaterials for Nanobattery and nanofuel cells
Inorganic Chemistry development in nanoparticle catalysts and applications thereof like gold nanoparticles, silver nanoparticles, iron and magnetic nanoparticles, quantum dots, and other metal /alloy nanoparticles.
Nanocatalysts for biotechnology and Nanomedicine – Chemistry of Drug delivery systems
BioNanocatalysts: Chemistry and Biology of Biocatalysts
All other subfields of Nanocatalysts development and application
The articles are invited from Chemical Sciences fraternity for publication in special issue. The Review articles, Original Research Articles, Short Communication, Expert Opinion would be considered for processing in the issue.
Submission: Authors need to submit their manuscript as per author guidelines on the journal Editorial Manager /manuscript processing site http://pubs.thesciencein.org/journal/index.php/jmns (or alternatively can be submitted by email at email@example.com )
Last Date of Submissions: January 30, 2019
Early Submissions (encouraged by): November 30, 2018
Issue Editing by
Dr. Rajender S. Verma,
U. S. Environmental Protection Agency
ORD, National Risk Management Research Laboratory
Water Systems Division/ Water Resources Recovery Branch
26 West Martin Luther King Drive, MS 443
Cincinnati, Ohio 45268, USA EB
Associate Editor and Senior Advisor
Research interest: NanoChemistry, Nanocatalysis, Nanoscience, nanomaterials.
Nanomaterials Frontiers is meant to cover exciting new and recent research advances in field of nanomaterials, smart materials development, new notable technological advances at nanometer scale research and path breaking research finding in nanomaterials advances. The Frontier research in nanomaterials covered from all literary sources highlighted as breakthrough findings in form of summarized reports ‘Nanomaterials Frontiers’ be published combined in print form of ‘Journal of Materials NanoScience’, however, selected highlights will be published online. The summarized highlights would provide a quick grasp of latest advances to scientists and young researchers.
Researchers are invited to submit the reports for covering in highlights/frontiers as small summary write up in simple lucid presentation (for easy understanding by novice researchers) extending upto 2 pages (the report should include new title and 2-3 paragraphs summary along with references to original source). Submit by email to pubs @ thesciencein .org or may submit by form below.
In this research work, we have synthesized blend of starch/PVA/nanoclay via solution cast method. The composition of blend was starch and PVA in 1:1 ratio by weight with citric acid as plasticizer. The amount of nanoclay was varied between 0.5 to 2 wt%. The structure elucidation of the film by Scanning electron microscopy reveals homogeneous dispersion of nanoclay into polymer matrix. The biodegradation of the films were studied by soil burial method and enzymatic hydrolysis and it was found that completely biodegradable films were produced which could serve as potential candidate for food packaging.
Herbal nanomedicine interactions to enhance pharmacokinetics, pharmaco-dynamics, and therapeutic index for better bioavailability and biocompatibility of herbal formulations
Rajiv Kumar University of Delhi
Munesh Sharma Arogya Nidhi Ayurveda Clinic
Keywords: Phyto-medicine, Hydrophilicity, Nanocarriers, Drug Delivery
The recent technological advancement in nanotechnology has opened new avenues for research and development in the field of phyto-medicine. Development of reliable and eco-friendly synthesis of nanoparticles is a significant advancement for introduction nanotechnology to develop noble nanomedical delivery system of herbs (HNMDS), and have to overcome the downsides of old-style herbs-medicines delivery through analyzing the interactions between nanocarriers and herbs or phyto-medicine. The application of nanotechnological methods for bioavailability and biocompatibility enhancement of phyto-medicine must be reviewed and need urgent prompt efforts to develop new formulations. Nanotechnology enables the combination of hitherto separate approaches to health care by permitting the realization of so-called ‘theranostic’ applications, as well as targeted combination products. Formulation must also release active ingredient from phyto-formulation as developing nano dosage forms has number of benefits for phyto-medicine. This review discusses nano sized herbs-nanomedicines delivery carries and potential current and futuristic advances for enhancing the activity and overcoming problems associated with herbal medicines for novel HNMDS.
The recent technological advancement in nanotechnology has unlocked new avenues for research and development in the field of phyto-medicine. Development of reliable and eco-friendly synthesis of nanoparticles is a significant advancement for starter nanotechnology to develop noble nanomedical delivery system of herbs (HNMDS), and have to overcome the downsides of old-style herbs-medicines delivery means through analyzing the interactions between nanocarriers and herbs or phyto-medicine. The application of nanotechnological ways and means for bioavailability and biocompatibility enrichment of phyto-medicine must be reread and need swift efforts to develop new formulations. Nanotechnology empowers the combination of hitherto separate approaches to health care by letting the realization of so-called ‘theranostic’ applications, as well as besieged blend products. Formulation must also release active ingredient from phyto-formulation as emerging nano dosage forms having number of benefits existed earlier in phyto-medicine. This assessment converses nano sized herbal nanomedicines delivery carries, potential current and ultramodern advances for enhancing the activity and overcoming problems associated with herbal medicines for the development of novel HNMDS. Clinical Pharmacokinetics is discussed in view of the impression of advance of drug absorption, distribution, metabolism, and excretion as per the entitlement of pharmacokinetic principles of the harmless and actual therapeutic applications of herbal nanomedical medications.
The two prominent diseases i.e Cancer and HIV infections has been putting a challenge to researchers community to find a reliable treatment. There have been newer developments and research advances in finding the cure for these by using chemistry biology interface research. To collect the advances in the filed, a special issue on anti-cancer and anti-HIV therapeutics development would be published in Chemical Biology Letters. The issue will cover the themes (though not limited to as field and research is wide):
– Kinase Inhibitor advances
– new targets for anti-cancer molecules
– development in anti-HIV therapeutics
– Medicinal Chemistry of Anti-Cancer drugs
– Medicinal Chemistry of anti – HIV molecules
– Development in drug delivery systems for anti-cancer and anti-HIV drugs
– Peptides based drug delivery
– Peptide therapeutics
– targeted drug delivery
– Small molecules and Heterocyclic molecules for anti-cancer and anti-HIV therapy
The Medicinal Chemistry community is invited to contribute a ‘Review Article’ ‘Research Article’ or ‘Short Communication’ for processing in special issue.
Last date for submission of manuscript: November 30, 2018.
Prof. Keykavous Parang
Associate Dean of Research, Graduate Studies, and Global Affairs
Professor of Medicinal Chemistry and Pharmacology
Harry and Diane Rinker Health Science Campus
9401 Jeronimo Rd.
Irvine, CA 92618-1908. USA
Dr. Rakesh Tiwari
School of Pharmacy (CUSP)
Harry & Diane Rinker Health Science Campus
9501 Jeronimo Road Rm 241
Irvine, CA 92618
Chemical Biology Letters is indexed in SCOPUS, CAS, CNKI, Google Scholar and other popular indexing databases.
Type-2 diabetes mellitus (T2DM) is a global disease, which leads to various other life threatening diseases and affects the quality of life. Current therapies of T2DM have various side effects and ultimately lead to insulin resistance, along with financial burden. Therefore, comparative study of natural compounds along with their mechanisms has been discussed, which may lead toward the better understanding about their efficacy and selection of future anti-diabetic drugs. Traditional medicine is promising to treat T2DM, where more than 200 plants and other species are shown to have anti-T2DM effects. Moreover, these natural products have different types of molecular mechanisms, i. e. β-cell regeneration, insulin mimicry, AMPK, Akt, PPARs, LXR activation and inhibition of α-glucosidase, TNF- α, sodium glucose co- tranporters and oxidative stress. At the same time numbers of compounds have been reported to have in vivo efficacy. As a number of investigators speculated the molecular mechanism of these natural opmpounds, hence this review is focused on the molecular mechanism of different types of natural anti-diabetic molecules and their classes along with their efficacy in animal models. This review will provide a broad idea about anti-diabetic compounds to scientific and common people and will help to choose the dietary components and traditional medicines effective in T2DM.