ispjournals

Impact of Ayurvedic drug Tinospora cordifolia in hyperlipidemia induced dysbiosis

Gut microbiota broadly impacts human health, but urinary microbial metabolites remain largely undefined. The concentration of microbial metabolites can be directly correlated with microbial populations in the human gut to define disease states. Tinospora cordifolia (Willd.) Miers ex Hook. F. & Thoms is being used for ages in the Indian ayurvedic system of medicine and it has hypolipidemic and hypoglycaemic activity. Present study investigate the MS-based metabolomics variations of possible gut microbiota associated metabolites in hyperlipidemia (HPL) and HPL treated with Tinospora cordifolia extract (TCE) (TRT). Twenty-four HPL male patients and 10 age-matched controls (HLT) were enrolled. Early morning fasting blood and urine samples were collected on days 0 and 14th of TCE treatment and subjected to lipid profiling and Q-TOF-MS analysis. Multivariate analysis showed urinary levels of urocanic acid, hydroxyphenylacetate, linolenic acid, phenylpropionate, hypoxanthine, and indole acetate produced by Peptostreptococcs asaccharolyticus, Clostridium difficile, Faecalibacterium prausnitzii, Bifidobacterium, Subdoligranulum, Lactobacillus, Clostridium sporogenes, E. coli were depleted in HPL patients as compared to healthy controls. In contrast, levels of serotonin, acetylleucine, hippuric acid, and arabinitol were found to be increased (>2.0 fold, p<0.005). However, TCE treatment reverted the levels of these metabolites and therefore, gut microflora. Also, Cloacibacterium haliotis, Lactobacillus, Clostridium, and Bifidobacterium population decreased in HPL patients. Increased secretion of yeast or Candida albicans associated metabolites was because of their increased population. Hence, TCE treatment enhanced the growth of useful gut microbiota in hyperlipidemia patients.

Scopus indexing status of Journal of Integrated Science and Technology

The Journal of Integrated Science and Technology is a peer reviewed international multidisciplinary journal meant for publication of quality research advances in different fields of science (Chemistry, Biology, Biotechnology, Pharmaceuticals Sciences, Physics, Materials Sciences, Environmental Science ) and technology fields (all engineering sub-disciplines).

The journal has been evaluated by Scopus board (Scopus Content Selection & Advisory Board (CSAB)) and accepted for indexing in Aug 2021. As a large number of queries arise from researchers regarding the indexing of this journal in scopus and other databases, so this document has been made available to provide the answer to FAQ about indexing of Journal of Integrated Science and Technology.

When a journal is submitted for indexing evaluation to scopus, the scopus team provides a tracking page to publisher for checking the progress of process and acceptance/rejection of respective journal. The tracking link for JIST is

https://suggestor.step.scopus.com/progressTracker/?trackingID=0E4ADDBEFFA932F4

The acceptance for indexing of JIST by scopus may be checked at above link (accepted on 29-Aug-2021 ).

Same details can be checked on the Sources details links provided by Scopus (see below image)

Download the excel file (as shown in the arrow in above image) and check the name of ‘Journal of Integrated Science and Technology’ in the downloaded MS-excel file to confirm the acceptance of journal for indexing by Scopus.

Further, the Scopus content indexing team has initiated the inclusion of JIST journal contents and has already indexed the one issue from year 2021. The scholars having the subscription access to Scopus (for content search – inside scopus) (may be through their institute) can search the name of ‘Journal of Integrated Science and Technology’ (in title source) for the total articles indexed in Scopus. For the reference to scholars that are not having the subscription access to scopus, a PDF print of search results has been provided below as the reference (the search and print was done on 1-feb-2022).

As the Scopus indexing team will include more articles from JIST in the Scopus database, the search results will show all the included articles.

Where is the problem, why the search with ISSN or journal name is not shown in Scopus?

Scholars generally search on the ‘Scopus Preview’ page https://www.scopus.com/sources (without subscription access) and do not find the ISSN/Name of the recently accepted journal. In actual, this page is meant for previewing the ‘matrices’ (citations to articles) of any journal. The Scopus generally releases journal matrices in the month of May or June, so till then the recently accepted journal will not reflect on this page (because journal matrices have not been calculated for that journal). Once the Scopus will provide the matrices (citations profile) for JIST journal, then it will be available for search (with ISSN and Name) on this (preview) page as well (probably after May 2022).

When my article published in JIST will be indexed by Scopus?

The Scopus content indexing support team continuously and periodically indexes the articles, however, we can’t provide an exact time for indexing, it may take 6 months or more/less depending upon when the Scopus team keeps the next round of indexing of respective journal contents.

My article published in JIST has not been indexed in Scopus while other articles from the year/volume are listed in Scopus?

You may contact the Scopus support for inclusion of your missing article/content. The details of procedure is provided on Scopus/elsevier page (click to see, use the form provided in step 2 to add content in database).

My article is missing in Scopus listing ?

Please refer previous question.

Can I, as Author, approach the Scopus to include/index my article published in JIST as my University/Institute requires the inclusion of my article in Scopus.

You may wait for some time as Scopus team will add the contents/articles themselves, however, for urgency you may use the link/form details on Scopus site (above).

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For any more specific queries, scholars may reach editorial office for details.

The Journal of Integrated Science and Technology

http://pubs.iscience.in/journal/index.php/jist

Author guidelines Applied NanoMedicine Journal

Information for Authors

> The Authors need to submit a single manuscript file containing all figures and tables.
> The supplementary data files should be submitted as a separate file.
> A cover letter and graphical abstract should be submitted along with manuscript as details provided below.

Cover letter

Authors should supply a cover letter indicating rational of their work. Cover letter should also have details of at least three reviewers (with email). Cover letter should be provided on the first step of submission in “Comments for Editor’ box.

Graphical Abstract

Authors need to submit a graphical abstract highlighting the contents of manuscript. The guidelines for graphical abstract preparation and submission are available on this link.

Manuscript

Manuscript should include Title, Author (s), Affiliation (complete name of institutions), Abstract, 5 Keywords, (other sections like Introduction, Results and discussion,  experimental procedures, conclusion in the main body text of manuscript could be used for full paper article), acknowledgment and references in the listed order. Short communications need not to be arranged in different sections. References should be formatted as shown for articles,1 theses,2 books,3,4 and patents,5

1. R. Ping, M. Laura, P.S. Mario. Title of the journal article should be included here. Int. Lett.Org. Chem. 1996, 61, 4439–4449.
2. B.K. Sharma. Ph.D. Dissertation, Thesis Title, Cornell University, 1995.
3. R. Hussain, D. Shinkoi. Title of book like Synthesis and application of ionic liquid, John Wiley & Sons: New York, 2010.
4. R.S. Buchanod, D.K. Reddy. In Selective Organic Transformations; T.R. Thyagarajan, Ed.; Integrated science: New York, 2002; Vol. 2, pp 1–95.
5. G.L. Loyale, U.S. Patent 5 934 456, 1998; Chem. Abstr. 1998, 65, 2870.

Citation Manager style files: Authors are highly encouraged to use the citation manager programs for citing and formatting the references. Authors may use Mendelay, Zotero, Paper 2 or Endnote program. If you are using any of these citation manager program for Bibliography (References and Notes), then you can download citation style file for journal (common for all ScienceIn journals):

Mendelay, Zotero, Paper 2 style file: ScienceIn Journals CSL style file

Authors can directly add the styles to Zotero and Mendeley, follow the below steps:
Zotero: Open Zotero desktop > Edit (top menu)> Preferences > Cite (menu in new opened small window) > Get additional styles.. (click this link below the list of styles) > in new opened window – search the term ‘Integrated Science’ in search box and then click on ‘Integrated Science Publishing Journals’ link > style file will download > Open the file with Zotero desktop and use (this style is common for all ScienceIn Journals).
Mendeley: Open Mendeley desktop > View (top menu) > Citation Styles > More styles.. > go to tab ‘Get more styles’ (in new opened window) > search for the term ‘Integrated Science’ in search box and then click on ‘install’ adjacent to ‘Integrated Science Publishing Journals’ list > style file will be installed > then click on ‘Use this style’ from the installed styles tab and use (this style is common for all ScienceIn Journals).

Endnote style file: ScienceIn Journals Endnote style file

(click and download the endnote style file from google drive … and either copy the file to Endnote style folder (go to C:>Program files>Endnote > Style folder > paste the file in this folder (it will listed in style when you open the Endnote program) or you can directly Open the downloaded style file in EndNote program and use).

Also the user can check the respective program user guide (online link on Zotero, Mendeley or Endnote) regarding information on how to use the style file.

Submission

Authors need to submit all manuscripts through journal website. Register by following link ‘Register’ above (make sure to mark checked the options Author and reviewer while registering for journal). On login, you will find ‘new submission’ link in your panel page.

For review purpose, author can submit the manuscript as outlined above. However, Authors are advised to prepare their manuscript according to journal article template (provided below) as it progress towards acceptance. On acceptance of manuscript, authors must need to supply their manuscript in Article template (if they have not already submitted in template). If you face difficulty in preparing manuscript according to template, then you can forward your manuscript (place all figures with caption in the end of file) to Copyeditor/Support department ( pubs@thesciencein.org )

Templates

On acceptance of manuscript, Authors are required to submit revised manuscript in journal articles template (If authors wish, they are free to submit their manuscript in journal article template while submitting first time).

Download the template, double click the file to open, prepare your article and save it with your own name.

Instructions for conversion of manuscript in journal article template is provided on https://pubs.thesciencein.org/manuscript-conversion-in-journal-article-template-instructions/  (please check the video on the link for correctly formatting your manuscript.

Login and submit the manuscript online (submission by email are not accepted). Only online submissions are accepted now.

Authors are advised to contact Support (email: pubs @ thesciencein.org ) if there is any problem in registration or submission.

Unique IDs for Articles: The journal is currently using URN number for the published articles (however, this is currently meant for internal use by journal). The journal will process the assigning of DOI (Digital Object Indentifier) to articles (including previously published ones) once the journal is indexed in Web of Science (Clarivate) as it help in providing the correct citations records for the published articles.

Declaration of Conflict of Interest

Authors should mention any conflict of interest in the work submitted to Applied Nanomedicine. The statement about conflict of interest may be mentioned in the ‘Letter to editor’ or placed in the manuscript after acknowledgement section.

Authors need to check the details of ‘Conflict of Interest’ for authors of scientific works.

Ethical Uses Declaration

If the manuscript report the experimentation on animals (including clinical trials on human beings), then declaration about ethical way handling of animals and about keeping the complete privacy of human identity (in case of clinical trials) must be mentioned in the manuscript.

Helsinki Declaration (contents from NIH-NLM): When reporting experiments on human subjects, authors should indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 (5). If doubt exists whether the research was conducted in accordance with the Helsinki Declaration, the authors must explain the rationale for their approach, and demonstrate that the institutional review body explicitly approved the doubtful aspects of the study. When reporting experiments on animals, authors should be asked to indicate whether the institutional and national guide for the care and use of laboratory animals was followed. See the detailed instructions on https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/  and https://www.wma.net/policy/current-policies/ (for recent applicable policy documents).

Authors need to check and follow the general Ethical Practices for Authors of scientific work.

Submission Journal Link

Submit manuscript on journal editorial processing site at

https://pubs.thesciencein.org/journal/index.php/nanomed  New site with new platform

Applied Nanomedicine Journal

Recent advances in Materials development and design for Gas Sensing applications

The detection of specific gases in different settings have emerged an essential requirement towards management of different sectors such as industries, agriculture, laboratories, supply chains etc. The development of sensors using different materials play pivotal role in application of gas sensors in real time conditions. Many different type of materials have been studied, utilized and applied for the development of gas sensors. The compilation of research advances in the field of new gas sensors would provide better understanding towards applications of advanced functional materials. The current compilation encompasses recent trends in the area of nanostructured gas sensors. Various aspects of developing a gas sensor such as materials synthesis, characterization and optimization of sensor parameters, gas sensing methodologies, mechanistic studies, theoretical modeling and real-life applications are discussed. The research advances in form of concise reviews and original research articles in different gas sensing areas have been covered. The current research direction in developing novel materials, various technologies adopted to advance the sensing capabilities in order to realize an end user preferred device is elucidated. This effort is aimed at providing various avenues to a researcher where research can be focused in order to develop a gas sensor.

Gas sensing of partially oxidized Ti3C2Tx MXene in argon atmosphere

Multilayer accordion like Ti3C2Tx MXene is prepared by selective etching of Al layer from Ti3AlC2 MAX phase.  For better gas sensing responses, a minimal amount of TiO2 decoration is being carried out by annealing the Ti3C2Tx MXene in an argon atmosphere at 550 °C for 6 h. The X-ray diffraction pattern shows successful removal of Al layer and TiO2 decoration on Ti3C2Tx MXene surface which is well supported by field emission scanning electron microscope images. Due to TiO2 decoration, MXene shows semiconducting behaviour and corresponding bandgap is 3.2 eV. Resistance of TiO2 decorated MXene sample increases in presence of H2, CH4 and NO2 gases at room temperature. However, resistance of the sample decreases for H2, and CH4 gases and increases for NO2 gas at 100 °C which shows n-type semiconducting behaviour. Also, at 100 °C, sensitivity increases by one order to that of room temperature gas response of TiO2 decorated MXene sample.  

Methane sensing studies of ex-situ oxidized sputtered V2O5 nanostructured films: Effect of post oxidation duration

The effect of microstructural modifications of V2O5 thin films, obtained through alterations in post oxidation duration, on methane sensing behavior is reported for the first time. Three different oxidation times viz., 1 h, 3 h and 5 h yielded varied microstructure and vibrational properties as evident from XRD and Raman investigation. These changes in properties manifest as differences in gas sensing behavior. Methane sensing properties of V2O5 was investigated in temperature range from 100 to 300 °C and optimum operating temperature of 200 °C was identified for all three samples. Films oxidized for 1 h showed the highest response due to favorable surface conditions which are discussed. These results will help in tailoring microstructure towards device level application processes. 

Recent progress in Nanostructured Metal Oxides based NO2 gas sensing in India

The metal oxides are considered as an outstanding semiconductor material to sense several toxicants from the environment. In particular, the nanostructure containing rod, wire, and tube-like morphology of metal oxides were widely utilized to fabricate effective gas sensors worldwide. Out of number of toxicant, nitrogen dioxide (NO2) is one of the highly reactive gas, results from the burning of fuel from vehicles, power plants, and off-road equipment.The exposures to NO2 may giverise to the development of the respiratory diseases and leads to the death. Therefore, the efficient detection of NO2 gas is the urgent need of recent era. More than 5000 research articles were published on the NO2 gas sensing worldwide. The researchers from India is also contributed a lot to detect the NO2 gas via nanostructured metal oxides powder and thin films. The aim of the present article is to explore the recent advances of NO2 gas sensors based on metal oxide nanomaterials within the country. The review begins with the general introduction of metal oxide, gas sensorand NO2 gas sensor and followed by the broadly discussion of major research groups working in India and their finding in the fieldof nanostructured metal oxide for the fabrication of NO2 gas sensors. Moreover, various factors likegas concentrations, working temperature, morphologies, sensor response, selectivity, etc. of metal oxides were discussed in the present report. The report concludes with the future directions and opportunities in the field of detection of NO2 gas in India and world.

A comprehensive review on functionalized Hydroxyapatite nanostructures based gas sensors for environmental pollutant monitoring

The utilization of advanced sensing techniques for detecting and monitoring toxic gases in industry and the environment is a predominant action. For such applications, the sensor material should possess higher sensitivity, faster detection, and real-time operation. Mostly, metal oxides (MOs) are preferred for gas sensing purposes owing to their excellent sensing property, wide band-gap, electrical conductivity, and high surface reactivity. But, the same MOs lag in many perspectives like low selectivity, higher operating temperature (> 400 °C), more power consumption, and reduced stability. Since more emphasis is given to materials that operate at room temperatures like nano-hydroxyapatite (nHAp), it’s a bio-ceramic material used for chemical gas sensing. The nHAp is a matrix of rich calcium (Ca2+) and phosphate (PO43-) ions. In chemical gas sensors, the nHAp possess significant properties like large surface phosphate-hydroxide (P-OH) groups, ionic conductivity, porous nature, and ion exchange capability for effective gas molecule interaction. In this profound review, we discussed the nHAp structure with different fabrication techniques for gas sensing. Particularly, functionalized nHAp with MO and polymers were focused and their stability, sensitivity, selectivity, and adsorption rate are presented along with different mechanisms. Existing challenges and future perspectives of nHAp material are also highlighted.

Defect mediated optical detection of ammonia using SnO2 nanoparticle

SnO2 with oxygen vacancies, an n-type gas sensing material used commercially as resistive sensors at high temperatures, suffers from the drift in voltage, contact resistances and poor selectivity. These prevailed defects in rutile SnO2 offer excellent optical properties which remain to be explored for the gas sensor. Apart from advantage of contactless operation with no direct voltage application, an optical method with the varied light energies is highly beneficial for excitations of the deep electronic states at ease, with opportunity to improve the sensor response measurement quickly in selective manner. In this direction, we report the synthesis and characterization of SnO2 nanostructures with emphasis on their Raman and photoluminescence properties. In subsequence, the crucial role of various defects in displaying the improved optical responses and selectivity for ammonia are highlighted.  

Genome-wide mutation/SNP analysis, biological characteristics, and Pan-India prevalence of SARS-CoV-2 Variants of Concern

The origin of COVID-19 pandemic, caused by SARS-CoV-2, was traced to Wuhan, China. Thereafter, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolved into various variants owing to genome-wide mutations, causing emergence of multiple variants, including Variant of Interest and Variant of Concern. Here, we discuss genomic architecture of SARS-CoV-2, as well as its multiple variants- alpha, beta, gamma, and delta, along with their biological properties, such as transmissibility, reduction in antibody-mediated neutralization, virulence, disease severity, vaccine effectiveness, and the prevalence across the India vis-à-vis world. Our data on VOC, pooled from the Global Initiative on Sharing All Influenza Data up to 31 October 2021, shows around 89% prevalence of delta VOC across various Indian States. Whereas alpha, beta, and gamma variants show 10.44%, 0.57%, and 0.11% prevalence, respectively. Compared with global scale, the reported Indian prevalence of alpha, beta, gamma, and delta are 0.40%, 0.63%, 0.04%, and 1.7%, respectively. Furthermore, prevalent vaccines of various natures show significantly reduced effectiveness against these VOCs, necessitating urgent need for development of effective prophylactic vaccines and potential therapy to contain the pandemic.