A comprehensive common Open Access policy has been enlisted with applicability to all ISP journals. Authors may refer to open access policy details for publication in ISP journal. The policy draft is available at
Murraya koenigii, commonly known as curry leaves, is a regular ingredient used in Indian cuisines. Not only it is beneficial for health but also it is speculated to have various medicinal properties. Although a large number of phytochemicals have been identified and tested for various properties but no compound have been extended for drug design purpose. Present work conducted on Murraya koenigii illustrates its anti-diabetic and anti-oxidant activities using various biochemical tests. From various evaluated leaf extracts of M.koenigii, DCM and Ethanol extracts were the one which showed best activity for anti-oxidant and anti-diabetic assays.
Herein we describe a simple method for the synthesis of Baylis-Hillman adducts and their acetates by utilizing inexpensively available cashew nut shell liquid (CNSL) natural resources. Furthermore, by using a molecular hybridization approach, a series of novel pyrimidine scaffolds (15a-15t) were synthesized via utilizing Baylis-Hillman acetates derived from cashew nut shell liquid (CNSL). All the newly synthesized compounds were screened for their in vitro antitumor activity. Baylis-Hillman compounds 5b and 5h showed promising anticancer activity against MCF-7. Among pyrimidine derivatives, compounds 15i, 15j and 15l showed promising activity against HEP-G2, whereas compounds 15j, 15k, 15l and 15m showed promising activity against MCF-7. In addition, compound 15m showed significant activity against K562 when compared with the standard. The structure-activity relationship (SAR) analysis suggests that the length of the carbon chain of phenyl ring played an important role in the potency of activity.
Professor Samir Kumar Pal,
Department of Chemical, Biological & Macromolecular Sciences,
S.N.Bose National Centre for Basic Sciences,
JD Block, Sector III, Salt Lake,
Kolkata (Calcutta), India
Expertise: Ultra-fast Spectroscopy in Bio molecules and Materials, Biomimetics, DSSC, Nanomedicines, Nano-catalysis, Development of Instruments for biomedical and environmental use.
> P. Kar, T. K. Maji, P. K. Sarkar, P. Lemmens and S. K. Pal. Development of a Photo-Catalytic Converter for Potential Use in the Detoxification of Cr(VI) Metal in Water from Natural Resources”, J. Mat. Chem. A (2018)
> P. K. Sarkar, A. Halder, A. Adhikari, N. Polley, S. Darbar, P. Lemmens and S. K. Pal
“DNA-based Fiber Optic Sensor for Direct In-vivo Measurement of Oxidative Stress”, Sensors & Actuators: B. Chemical 255 (2018) 2194
> P. Singh, S. Choudhury, S. Kulanthaivel, D. Bagchi, I. Banerjee, S. A. Ahmed, and S. K. Pal
“Photo-triggered Destabilization of Nanoscopic Vehicles by Dihydroindolizine for Enhanced Anticancer Drug Delivery in Cervical Carcinoma”, Colloids and Surfaces B: Biointerfaces 162 (2018) 202
> A. Halder, P. K. Sarkar, P. Pal, S. Chakrabarti, P. Chakrabarti, D. Bhattacharyya, R. Chakraborty and S. K. Pal
“Digital Camera Based Spectrometry for the Development of Point-of-Care Anemia Detection on Ultra-low Volume Whole Blood Sample”, IEEE Sensors Journal 17 (2017) 7149.
> J. Patwari, S. Sardar, B. Liu, P. Lemmens and S. K. Pal
“Three in One Approach Towards Efficient Organic Dye Sensitized Solar Cells: Anti-aggregation, Panchromatic Absorption and Resonance Energy Transfer”, Beilstein J. Nanotechnology 8 (2017) 1705.
> P. K. Sarkar, A. Halder, N. Polley and S. K. Pal
“Development of Highly Selective and Efficient Prototype Sensor for Potential Application in Environmental Mercury Pollution Monitoring”, Water, Air, & Soil Pollution 228 (2017) 314.
> P. Kar, T. K. Maji, J. Patwari and S. K. Pal
“Can A Light Harvesting Material be Always Common in Photocatalytic and Photovoltaic Applications?”, Materials Chemistry and Physics 200 (2017) 70.
> A. Mazumder, S. Batabyal, M. Mondal, T. Mondol, S. Choudhury, R. Ghosh, T. Chatterjee, D. Bhattacharyya, S. K. Pal, and S. Roy “Specific DNA Sequences Allosterically Enhance Protein-Protein Interaction in a Transcription Factor through Modulation of Protein Dynamics: Implications for Specificity of Gene Regulation”, Phys. Chem. Chem. Phys. 19 (2017) 14781.
> R. Nandi, S. Mishra, T. K. Maji, K. Manna, P. Kara, S. Banerjee, S. Dutta, S. K Sharma, P. Lemmens, K. Das Saha and S. K. Pal “A Novel Nanohybrid for Cancer Theranostics: Folate Sensitized Fe2O3 Nanoparticle for Colorectal Cancer Diagnosis and Photodynamic Therapy”, J. Mat. Chem. B 5 (2017) 3927.
> P. Singh, S. Choudhury, S. Dutta, A. Adhikari, S. Bhattacharya, D. Pal and S. K. Pal
“Ultrafast Spectroscopy on DNA-Cleavage by Endonuclease in Molecular Crowding”, Int. J. Biol. Macromolecules 103 (2017) 395.
> P. K. Sarkar, S. Pal, N. Polley, R. Aich, A. Adhikari, A. Halder, S. Chakrabarti, P. Chakrabarti and S. K. Pal
“Development and Validation of a Noncontact Spectroscopic Device for Hemoglobin Estimation at Point-of-Care”, J. Biomed. Optics 22 (2017) 055006.
> P. Singh, S. Choudhury, S. Singha, Y. Jun, S. Chakraborty, J. Sengupta, R. Das, K-Han Ahn and S. K. Pal. “A Sensitive Fluorescence Probe for the Polar Solvation Dynamics at Protein- Surfactant Interface”, Phys. Chem. Chem. Phys. 19 (2017) 12237.
> D. Bagchi, S. Dutta, P. Singh, S. Chaudhuri and S. K. Pal. “Essential Dynamics of an Effective Phototherapeutic Drug in a Nanoscopic Delivery Vehicle: Psoralen in Ethosome for Biofilm Treatment”, ACS Omega 2 (2017) 1850.
> S. Mondal, A. Giri, Y. Zhang, S. K. Pal, W. Zhou and L-ping Wen “Caspase mediated beclin-1 dependent autophagy tuning activity and apoptosis promotion by surface modified hausmannite nanoparticle”, J. Biomed. Mat. Res.: A 105 (2017) 1299.
> A. Adhikari, N. Polley, S. Darbar and S. K. Pal “Therapeutic Potential of Surface Functionalized Mn3O4 Nanoparticles against Chronic Liver Diseases in Murine Model”, Materials Focus 3 (2017) 280.
> S. Ghosh, P. Kar, N. Bhandary, S. Basu, T. Maiyalagan, S. Sardar and S. K. Pal “Reduced graphene oxide supported hierarchical flower like manganese oxide as efficient electrocatalysts toward reduction and evolution of oxygen”, Int. J. Hydrogen Energy 42 (2017) 4111.
> Z. S. Seddigi, S. A. Ahmed, S. Sardar, N. H. Yarkandi, M. Abdulaziz and S. K. Pal “Combating Fuel-driven Aqua-Pollution by �BenzoMagnets�”, RSC Advances 7 (2017) 12277.
> D. Bagchi, T. K. Maji, S. Sardar, P. Lemmens, C. Bhattacharya, D. Karmakar and S. K. Pal “Sensitized ZnO Nanorod assemblies to detect heavy metal contaminated phytomedicines: Spectroscopic and Simulation Studies”, Phys. Chem. Chem. Phys. 19 (2017) 2503.
> T. K. Maji, D. Bagchi, P. Kar, D. Karmakar and S. K. Pal “Enhanced Charge Separation through Modulation of Defect-state in Wide Band-gap Semiconductor for Potential Photocatalysis Application: Ultrafast Spectroscopy and Computational Studies”, J. Photochem. Photobiol. A 332 (2017) 391.
> P. Kar, T. K. Maji, R. Nandi, P. Lemmens and S. K. Pal. “In-situ hydrothermal synthesis of Bi-Bi2O2CO3 heterojunction photocatalyst with enhanced visible light photocatalytic activity”, Nano-Micro Letters 9 (2017) 18.
> J. Patwari, H. Ghadi, S. Sardar, J. Singhal, B. Tongbram, S. Shyamal, C. Bhattacharya, S. Chakrabarti and S. K. Pal
“Photo-induced electronic properties in single quantum well system: Effect of excitonic lifetime”, Materials Res. Express 4 (2017) 016301.
Prof. Pal is associated with ‘Journal of Materials NanoScience’ as Editorial Advisory Board Member since 2014. The journal link is http://www.pubs.iscience.in/journal/index.php/jmns
The Journal for NanoScience and Nanotechnology Education or Nanoeducation literature have been included in section part of ‘Journal of Materials NanoScience‘ under NanoEdu section.
The faculty members now can published their literary work required for teaching and learning of NanoScience and Nanotechnology concepts. The following type of work will be considered for publication
Lecture Notes: for undergraduate level or postgraduate level, systemic write ups for better understanding of nano concepts.
Chapters : Detailed chapters in field of nanomaterials, NanoScience, nanotechnology.
Practical experimental details: If you are conducting experiments as part of curriculum study, then you can submit the details of experiments for undergraduate as well as postgraduate courses. This has to include complete details for repeat-ability by the students (step wise complete procedure explanation besides theory of experimentation)
Submission of manuscript:
The chapters or NanoEdu articles should be prepared as per journal guidelines and submit on the journal site in NanoEdu section. Authors may prepare the articles in the journal article template provided under author guidelines section, however, the final font size and layout of manuscript would be updated for clear presentation of contents and easy readability for readers. The manuscripts will be peer reviewed publication.
Journal site: http://www.pubs.iscience.in/journal/index.php/jmns
When suitable number of articles on particular theme would have been published in the NanoEdu section of the journal, then these will also be compiled and published as book.
This collective compilation would be highly beneficial for students of nanosciences/nanotechnology subject in all countries. SUBMIT YOUR MANUSCRIPT TODAY
Rajender S. Varma, Ph.D.
U. S. Environmental Protection Agency
ORD, National Risk Management Research Laboratory
Water Systems Division/ Water Resources Recovery Branch
26 West Martin Luther King Drive, MS 443
Cincinnati, Ohio 45268, USA
Prof. Rajender (Raj) S. Varma (H -Index 96) was born in India (Ph.D., Delhi University 1976). After postdoctoral research at Robert Robinson Laboratories, Liver-pool, UK, he was faculty member at Baylor College of Medicine and Sam Houston State University prior to joining US Environmental Protection Agency (EPA) in 1999 with affiliation at Palacky University, Olomouc, Czech Republic (2014). He has over 45 years of experience in management of multi-disciplinary technical programs and is extensively involved in sustainable aspects of chemistry that includes, development of environmentally benign methods using alternate energy input using microwaves, ultrasound, photochemistry and mechano-chemistry and efficient technologies for the sustainable remediation of contaminants in the environment. Lately, he has focused on greener approaches to assembly of nanomaterials and sustainable applications of magnetically retrievable nano-catalysts in benign media. Dr. Varma has received numerous awards: Office of Research and Development (ORD) Sustainability Award (2015) from US EPA; Silver Medal for Superior Service-EPA for outstanding scientific and leadership contributions establishing EPAas a pioneering organization in Green Chemistry (2013), Visionary of the Year Award -Green Technology for Environment (2009), among others. He is on editorial advisory board of several international journals and has published over 465 scientific papers and awarded 16 US Patents, 8 books, 27 book chapters and 3 encyclopedia contributions with over ~ 31,000 citations.
Publications: Selected from ~465 Peer-reviewed Papers, 7 Books, 28 Book Chapters and 3 Encyclopedia contributions; (~388 Presentations in National and International meetings).
Kou, J.,J. Wang,W. Sun, C. Lu, Z. Xuand R. S. Varma. 2017. Selective Enhancement in Heterogeneous Photocatalytic Transformations. Chemical Reviews,117:1445-1514.
Verma, S., R. B. Nasir Baig, M. N. Nadagouda, C. Len and R. S. Varma. 2017. Sustainable Pathway to Furanics from Biomass via Heterogeneous Organo-Catalysis.Green Chemistry,19:164-168.
Varma, R. S. 2016. Greener and Sustainable Trends in Synthesis of Organics and Nanomaterials. ACS Sustainable Chemistry and Engineering,4:5866-5878.
Gawande, M. B., A. Goswami, F.-X. Felpin, T. Asefa, X. Huang, R. Silva, X. Zou, R. Zboril, and R. S. Varma. 2016.Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis. Chemical Reviews,116:3722-3811.
Verma, S., R. B. Nasir Baig, M. N. Nadagouda and R. S. Varma. 2016. Visible Light Mediated Upgrading of Biomass to Biofuel. Green Chemistry,18:1327-1333.
Nasir Baig, R. B., S. Verma, M. N. Nadagouda and R. S. Varma. 2016. A Photoactive Bimetallic Framework for Direct Aminoformylation of Nitroarenes. Green Chemistry, 18:1019-1022.
Sharma, V. K., J. Filip, R. Zboril, and R. S. Varma. 2015. Natural Inorganic Nanoparticles – Formation, Fate, and Toxicity in the Environment. Chemical Society Reviews,44:8410-8423.
Gawande, M. B., A. Goswami, T. Asefa, H. Guo, A. V. Biradar, D.-L. Peng, R. Zboril, and R. S. Varma. 2015. Core-Shell Nanoparticles: Synthesis and Applications in Catalysis and Electrocatalysis. Chemical Society Reviews,44:7540-7590.
Sharma, V. K.,R. Zboril, and R. S. Varma. 2015. Ferrates: Greener Oxidants with Multimodal Action in Water Treatment Technologies. Accounts of Chemical Research,48:182-191.
Nasir Baig, R. B., M. N. Nadagouda and R. S. Varma. 2015. Magnetic Retrievable Catalysts for Asymmetric Synthesis. CoordinationChemistry Reviews,287:137-156.
Prucek R., J. Tuček, J. Kolařík, I. Hušková, J. Filip, R. S. Varma, V. K. Sharma, and R. Zbořil. 2015. Ferrate (VI)-Prompted Removal of Metals in Aqueous Media: Mechanistic Delineation of Enhanced Efficiency via Metal Entrenchment in Magnetic Oxides. Environmental Science and Technology,49:2319-2327.
GawandeM. B., S. Shelke, R. Zboril and R. S. Varma. 2014. Microwave-Assisted Chemistry: Synthetic Applications for Rapid Assembly of Nanomaterials and Organics. Accounts of Chemical Research,47:1338-1348.
VarmaR. S. 2014. Journey on Greener Pathways: From the use of Alternate Energy Inputs and Benign Reaction Media to Sustainable Applications of Nano-Catalysts in Synthesis and Environmental Remediation. Green Chemistry,16:2027-2041.
Dr. RS Verma is associated with Journal of Materials nanoScience as Editorial Advisory Board member. The journal link is http://www.pubs.iscience.in/journal/index.php/jmns
Dr. Asish Pal
Institute of Nano Science and Technology, Phase – 10, Sector – 64, Mohali, Punjab, India. EB, R
Research Interest: Supramolecular chemistry, Micelles, Dynamic Covalent chemistry, Hydrogel, Nanocatalysis, Nanomolecule Probes.
Dr. S. Balakumar
National Centre for Nanoscience and Nanotechnology
University of Madras Maraimalai (Guindy) Campus
Dr. Balakumar is the director of National Centre for Nanoscience and Nanotechnology, Madras University. He has several awards and patents to his credit such as IME Team Excellence Award on Nanowires project, 2008
IME Long Term Service award, 2007
IEEE Senior Membership Award, 2004
JSPS Fellowship, Japan 2000
STA Fellowship, 2001
NSTB Fellowship by Singapore A-Star -1997-1999
CUHK University fellowship (1995-97)
CSIR Research Fellowship to carry out Ph.D, 1994
CSIR Travel Award to attend IMf1993, USA
DST Full Travel Award to attend and Chair MRS 2009
US Patents : High Speed Nanowire Semiconductor Devices based on Hetero structure and formation of Such ( Patent filed, 2007)
U.S. Patent:High K artificial lattices for capacitor applications to use in CU or AL BEOL, Patent No. 6,830,971
U.S. Patent Linear polishing for improving substrate uniformity, U. S Patent: 6,726,545, April 27, 2004
U.S. Patent: Multiple steps CMP polishing, U. S Patent: 6,663,472, December 16, 2003
U.S. Patent: Method to form shallow trench isolations, U.S. Patent: 6,649,486 , November 18, 2003
U.S. Patent: Method for improving oxide erosion of tungsten CMP operations, U. S. Patent: 6,569,770,, May 27, 2003
U.S. Patent: CMP uniformity, U.S. Patent: 6,248,006 June 19, 2001.
His research interests are Multifunctional Nanomaterials, Multiferroics nanomaterials, Metal Oxide Nanostructures for sensor and Photocatalytic application, Micro/Nanoelectronic Fabrication Processes, Cu-interconnects, Chemical Mechanical Planarization and Clean technology, Nanobioglasses for medical applications.
Dr. Balakumar is associated with ‘Journal of Materials NanoScience‘ as Editorial Advisory Board Member.
Guest Editorial for special issue on Nuclear Medicine