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nano regenrative medicine

Nanobiomaterials, nanobiomechanics and tissue bioengineering for advanced regenerative therapeutics: present and future perspectives

Rajiv Kumar, Sandeep Mittan, Jyoti Singh

Abstract


Nanobiomaterials and nanotechnology explore the fundamentals of nanoscale materials properties to develop new possibilities in the area of tissue bioengineering and regenerative therapy. Interestingly, the fundamental research advances in the field of chemistry and material science further improve the potential applicability in this field. The scientific advances, fostered by close molecular interaction evaluations provide a basis for advancing nanotechnology, nanomaterials, and nanobiomaterials to utilize in tissue bioengineering and the development of regeneration therapy. Interdisciplinary research in the field of nanotechnology can boost these possibilities of advancement and can be further applied to enhance the regenerative potential of biomaterials. The innovations and research advances in bio-Interfaces, drug delivery, and nanobiotechnology improve the efficacy of present methodologies and future potential applications. Research developments in bio-interfaces explore a molecular-level understanding of complex biological systems and help to achieve the controlled release of nanotherapeutic agents on the desired site. The emerging fields of nanobiotechnology, tissue bioengineering, and regenerative medicine assimilate for better molecular assemblies as required to apply nanoscale strategy to comprehend the machinery of biological routes. The nano-bio tools (nanosized pores, grooves, and ridges) have been designed and developed for regenerative therapies for the regeneration of bone, muscle, neural tissue, vascular, cartilage, bladder, and brain tissue for years. These tools and devices are capable to enhance the cellular microenvironment for remodeling functional tissues essential for repairing the damaged cells and tissues. The emerged nano-bio interfaces are capable to promote the transportation of biomolecules (monoclonal antibodies, receptor-specific peptides, proteins, folates, vitamins, and carbohydrates) as desired to boost up regeneration processes

Keywords


Regeneration; Nanomedicine; Tissue Engineering; Nanobiotechnology; Nanotools;

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