chromone derivatives

Synthesis and antibacterial studies of 3-substituted chromone derivatives.

Savita Chahal, Krishan Kumar Selwal, Sonia Nain


A series of 3-substituted chromone derivatives have been synthesized. All of the synthesized compounds have been characterized from their spectral data and tested their antibacterial activity against both gram-positive as well as gram-negative bacteria. The activity results revealed that all the compounds examined displayed good activity against all the pathogenic bacterial strains studied with zone of inhibition 16-20 mm and MIC values in the range of 50–100 µg/mL as compared to the standard used. 


Chromone; Vilsmeier-Haack formylation; Antibacterial activity; Zone of Inhibition; MIC;

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